Excel HowTO

1. Import data from file

You could use copy and paste, it would pop up a import dialog, so you could choose the separation symbol, E.g. Space or tab

2. set the function you want to use

E.g. substraction
click on the rectangle where you want to put the result at
type: "=F1-D1", Enter
if you want to apply this function to other rows, just drag the result rectangle

E.g. average
Click on the rectangle where you want to put the result at
type "=AVERAGE(F27:F36)", Enter

Remember, if you start with "=", it would assume it is a function, you could also search the function.